Fig. 2

A&P prevented renal inflammation in diabetic nephropathy mice. a-c, A&P admnistration effectivly reduced the mRNA expression of TNF-α, IL-1β and IL-6 in DN mice. d-h, The relative expression of p-NFκB detected by western boltting analysis normalized to NFκB expression, and the relative expression of TNF-α, IL-1β and IL-6 detected by western boltting analysis normalized to β-actin expression. i, Immunoflfluorescence staining of TNF-α, IL-1β and IL-6 in kidney of DN mice. (The data are expressed as the mean ± SD. Compared with NC group, *P < 0.01. Compared with DN group, ^#P < 0.05, ^##P < 0.01)