Network pharmacology and in vitro studies reveal the pharmacological effects and molecular mechanisms of Shenzhi Jiannao prescription against vascular dementia

Tian, Danfeng; Gao, Qiang; Chang, Ze; Lin, Jingfeng; Ma, Dayong; Han, Zhenyun

doi:10.1186/s12906-021-03465-1

BMC Complementary Medicine and Therapies

Table 1 Potential active components of Ginseng, Anemarrhenae and Paeoniae rubra

From: Network pharmacology and in vitro studies reveal the pharmacological effects and molecular mechanisms of Shenzhi Jiannao prescription against vascular dementia

Herb	Mol ID	Molecule Name	MW	OB (%)	DL
Ginseng	MOL005348	Ginsenoside-Rh4_qt	458.8	31.11	0.78
Ginseng	MOL005357	Schisantherin B	514.62	31.99	0.83
Ginseng	MOL005376	Panaxadiol	460.82	33.09	0.79
Ginseng	MOL005344	Ginsenoside Rh2	622.98	36.32	0.56
Ginseng	MOL000358	beta-Sitosterol	414.79	36.91	0.75
Ginseng	MOL005399	alexandrin_qt	414.79	36.91	0.75
Ginseng	MOL004492	Chrysanthemaxanthin	584.96	38.72	0.58
Ginseng	MOL005317	Deoxyharringtonine	515.66	39.27	0.81
Ginseng	MOL005401	Ginsenoside Rg5_qt	442.8	39.56	0.79
Ginseng	MOL002879	Diisooctyl phthalate	390.62	43.59	0.39
Ginseng	MOL000449	Stigmasterol	412.77	43.83	0.76
Ginseng	MOL005384	Suchilactone	368.41	57.52	0.56
Ginseng	MOL005360	Malkangunin	432.56	57.71	0.63
Ginseng	MOL000787	Protopine	353.4	59.26	0.83
Ginseng	MOL003648	(+)-Maackiain	284.28	65.83	0.54
Ginseng	MOL005321	Frutinone A	264.24	65.9	0.34
Ginseng	MOL005314	Celabenzine	379.55	101.88	0.49
Anemarrhenae	MOL001677	Aurantiamide acetate	444.57	58.02	0.52
Anemarrhenae	MOL003773	Mangiferolic acid	442.75	36.16	0.84
Anemarrhenae	MOL000422	Kaempferol	286.25	41.88	0.24
Anemarrhenae	MOL004373	Icaritin	368.41	45.41	0.44
Anemarrhenae	MOL004489	Anemarsaponin F_qt	432.71	60.06	0.79
Anemarrhenae	MOL004492	Chrysanthemaxanthin	584.96	38.72	0.58
Anemarrhenae	MOL004497	Hippeastrine	315.35	51.65	0.62
Anemarrhenae	MOL004514	Timosaponin B III_qt	416.71	35.26	0.87
Anemarrhenae	MOL000449	Stigmasterol	412.77	43.83	0.76
Anemarrhenae	MOL004528	Icariin	676.73	41.58	0.75
Anemarrhenae	MOL004540	Anemarsaponin C_qt	416.71	35.5	0.87
Anemarrhenae	MOL004542	Anemarsaponin E_qt	448.76	30.67	0.86
Anemarrhenae	MOL000483	N-cis-FeruloyltyraMine	313.38	118.35	0.26
Anemarrhenae	MOL000546	Diosgenin	414.69	80.88	0.81
Anemarrhenae	MOL000631	cis-N-p-Coumaroyltyramine	283.35	112.9	0.2
Paeoniae rubra	MOL001910	11alpha,12alpha-Epoxy-3beta,23-dihydroxy-30-nor-olean-20(29)-en-28,13beta-olide	470.71	64.77	0.38
Paeoniae rubra	MOL001918	Paeoniflorgenone	318.35	87.59	0.37
Paeoniae rubra	MOL001919	Palbinone	358.52	43.56	0.53
Paeoniae rubra	MOL001921	Lactiflorin	462.49	49.12	0.8
Paeoniae rubra	MOL001924	Paeoniflorin	480.51	53.87	0.79
Paeoniae rubra	MOL001925	Paeoniflorin_qt	318.35	68.18	0.4
Paeoniae rubra	MOL001928	Albiflorin_qt	318.35	66.64	0.33
Paeoniae rubra	MOL001930	Benzoylpaeoniflorin	584.62	31.27	0.75
Paeoniae rubra	MOL000211	Betulinic acid	456.78	55.38	0.78
Paeoniae rubra	MOL000358	beta- Sitosterol	414.79	36.91	0.75
Paeoniae rubra	MOL000359	Sitosterol	414.79	36.91	0.75
Paeoniae rubra	MOL000422	Kaempferol	286.25	41.88	0.24
Paeoniae rubra	MOL000492	(+)-Catechin	290.29	54.83	0.24

Back to article page

ISSN: 2662-7671

Contact us

Submission enquiries: bmccomplementarymedicineandtherapies@biomedcentral.com
General enquiries: ORSupport@springernature.com