Fig. 3

Effect of sino on inflammatory response pathways. Cells were pretreated with sin, Dex, and sino for 2 h, and then treated with 1 μg/ml LPS for 24 h. a Western blot analysis of phosphorylated NF-κB (a), phosphorylated MAPK (b), iNOS (c) and COX-2 (e) expression in RAW264.7 cells. qPCR analysis of iNOS (d) and COX-2 (f) in cells. The values are presented as the mean ± SD (n = 3), ^*p < 0.05, ^**p < 0.01compared with LPS group; △p < 0.05, △△p < 0.01 compared with con group, ;^#p < 0.05, ^##p < 0.01 compared with sin group