Table 6 Effects of M. pruriens extract on lipid peroxidation (MDA) level and total protein in the liver and kidney of rats after CCl₄ and rifampicin induced toxicity

Malonidialdehyde (MDA) (mM/g tissue)

Liver

0.23 ± 0.01^a

0.42 ± 0.01

0.35 ± 0.01^a

0.25 ± 0.01^a

0.20 ± 0.01^a

0.58 ± 0.01

0.36 ± 0.02^a

0.25 ± 0.02^a

Kidney

0.89 ± 0.01^a

1.76 ± 0.03

1.23 ± 0.01^a

1.09 ± 0.02^a

1.02 ± 0.01^a

0.94 ± 0.01

0.52 ± 0.01^a

0.47 ± 0.03^a

Serum

0.64 ± 0.02^a

1.55 ± 0.01^a

0.70 ± 0.02^a

0.60 ± 0.07^a

0.59 ± 0.04^a

1.04 ± 0.09

0.63 ± 0.01^a

0.58 ± 0.01^a

Total Protein (mg/g tissue)

Liver

2.64 ± 0.16^a

1.47 ± 0.19

2.07 ± 0.42^a

2.15 ± 0.17^a

2.33 ± 0.78^a

1.04 ± 0.09

1.63 ± 0.02^a

2.53 ± 0.01^a

Kidney

1.73 ± 0.020^a

0.76 ± 0.06

0.89 ± 0.01^a

1.24 ± 0.01^a

1.44 ± 0.07^a

1.06 ± 0.01

1.20 ± 0.01^a

1.46 ± 0.02^a

Serum

2.08 ± 0.08^a

1.26 ± 0.06

1.81 ± 0.01^a

1.74 ± 0.01^a

2.17 ± 0.08^a

1.02 ± 0.18

1.15 ± 0.13^a

1.88 ± 0.20^a