Parameters | Tissues | Negative Control | Positive Control (CCl4 only) | CCl4 + 50 mg/kg b.w MP | CCl4 + 100 mg/kg b.w MP | CCl4 + 100 mg/kg b.w Silymarin | Negative Control II (Rifampicin only) | Rifampicin + 50 mg/kg b.w MP | Rifampicin + 100 mg/kg b.w MP |
---|---|---|---|---|---|---|---|---|---|
T. Chol (mg/dl) | Liver | 56.08 ± 2.09a | 89.12 ± 1.73 | 64.22 ± 1.23a | 53.25 ± 1.06a | 52.33 ± 1.34a | 97.23 ± 1.42 | 66.40 ± 2.15a | 58.29 ± 1.76a |
Kidney | 30.07 ± 2.18a | 41.86 ± 2.09 | 33.22 ± 2.03a | 27.63 ± 1.97a | 38.63 ± 2.23a | 53.24 ± 1.03 | 46.32 ± 1.23a | 34.04 ± 1.16a | |
Serum | 52.16 ± 2.19a | 72.44 ± 1.86 | 61.32 ± 1.36a | 56.82 ± 1.45a | 58.27 ± 1.56a | 87.46 ± 1.38 | 64.03 ± 1.02a | 59.34 ± 2.16a | |
Trig. (mg/dl) | Liver | 41.33 ± 1.07a | 70.25 ± 1.24 | 51.27 ± 1.39a | 43.76 ± 1.22a | 39.43 ± 1.13a | 86.50 ± 0.42 | 71.49 ± 0.63a | 60.08 ± 1.23a |
Kidney | 11.82 ± 0.34a | 19.47 ± 0.42 | 14.06 ± 0.77a | 12.93 ± 0.64a | 13.43 ± 0.29a | 26.48 ± 0.33 | 20.13 ± 0.29a | 16.25 ± 0.20a | |
Serum | 37.51 ± 1.39a | 61.41 ± 1.28 | 50.14 ± 1.07a | 42.66 ± 1.33a | 40.14 ± 1.72a | 70.39 ± 1.45 | 53.86 ± 2.09a | 46.25 ± 1.77a | |
HDL (mg/dl) | Liver | 24.72 ± 0.44a | 16.07 ± 0.53 | 20.15 ± 0.68a | 22.43 ± 0.53a | 26.31 ± 0.59a | 18.26 ± 0.24 | 21.72 ± 0.66a | 23.18 ± 0.52a |
Kidney | 8.26 ± 0.17a | 5.31 ± 0.87 | 8.12 ± 0.56a | 8.51 ± 0.53a | 8.42 ± 0.68a | 6.08 ± 0.63 | 6.83 ± 0.53a | 7.27 ± 0.76a | |
Serum | 9.42 ± 0.31a | 6.37 ± 0.43 | 7.00 ± 0.81a | 7.82 ± 0.70a | 8.79 ± 0.29a | 5.10 ± 0.07 | 8.15 ± 0.05a | 8.86 ± 0.02a | |
LDL (mg/dl) | Liver | 33.76 ± 1.27a | 41.27 ± 1.53 | 36.09 ± 1.31a | 32.47 ± 0.78a | 33.04 ± 0.62a | 57.81 ± 0.11 | 48.06 ± 0.37a | 39.16 ± 0.25a |
Kidney | 13.26 ± 0.73a | 21.60 ± 0.82 | 16.01 ± 0.69a | 14.07 ± 0.43a | 12.13 ± 0.48a | 31.27 ± 0.57 | 24.12 ± 0.54a | 19.33 ± 0.66a | |
Serum | 22.36 ± 0.32a | 34.26 ± 0.53 | 26.42 ± 0.34a | 22.14 ± 0.13a | 24.67 ± 0.72a | 39.53 ± 0.68 | 30.06 ± 0.51a | 23.72 ± 0.44a |