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Table 2 MIC and MFC values obtained for Candida spp. reference strains and clinical isolates incubated with different concentration of four propolis extracts. Candida spp. strains and clinical isolates were incubated for 48 h with different concentrations of the four propolis extracts, and the growth inhibition was then calculated. MIC: Minimal Inhibitory Concentration; MFC: Minimal Fungicidal Concentration; GP_EtOH: green propolis ethanolic extract; GP_US: green propolis ethanolic extract pre-treated with ultrasound; RP_EtOH: red propolis ethanolic extract; RP_US: red propolis ethanolic extract pre-treated with ultrasound

From: Activity of antifungal drugs and Brazilian red and green propolis extracted with different methodologies against oral isolates of Candida spp.

Isolate

Species

GP_EtOH

(mg/mL)

GP_US

(mg/mL)

RP_EtOH

(mg/mL)

RP_US

(mg/mL)

MIC

MFC

MIC

MFC

MIC

MFC

MIC

MFC

2508

C. albicans

2

4

4

> 8

1

2

2

2

2517

C. albicans

4

4

2

2

0.5

1

1

2

3703

C. albicans

4

8

4

> 8

0.5

4

2

4

3704

C. albicans

4

8

2

4

0.5

2

0.25

2

PAC 01

C. dubliniensis

2

4

2

> 8

1

2

2

2

PAC 02

C. tropicalis

4

> 8

2

2

1

4

0.015

2

PAC 04

C. tropicalis

1

4

1

2

0.125

1

1

2

PAC 05

C. tropicalis

4

> 8

8

> 8

1

2

2

2

PAC 06

C. albicans

> 8

> 8

> 8

> 8

4

> 8

2

> 8

PAC 08

C. albicans

> 8

> 8

> 8

> 8

> 8

> 8

2

> 8

PAC 13

C. albicans

> 8

> 8

4

> 8

4

4

1

> 8

PAC 15

C. tropicalis

> 8

> 8

> 8

> 8

4

> 8

2

2

PAC 17

C. albicans

> 8

> 8

> 8

> 8

2

> 8

1

2

PAC 18

C. albicans

> 8

> 8

> 8

> 8

2

> 8

2

2

PAC 19

C. albicans

> 8

> 8

> 8

> 8

1

1

0.015

0.125

PAC 20

C. albicans

> 8

> 8

4

> 8

1

2

1

2