Skip to main content
Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice

Fig. 8

DISS promoted the proliferation of hippocampal NSCs in APP/PS1 mice. IF analysis against Sox-2 and Nestin was carried out to detect the NSCs in the hippocampus of APP/PS1 mice. (A) Representative immunostaining images of Sox-2+ cells in the hippocampal DG areas. (B) Quantitative analysis of Sox-2+ cells. (C) Representative immunostaining images of Nestin+ cells in the hippocampal DG areas. (D) Quantitative analysis of Nestin+ cells. ##P < 0.01 vs. WT group; *P < 0.05 vs. APP/PS1 group. Scale bar = 100 μm. Data are represented as mean ± sem. n = 6 mice in each group; six slices per animal analyzed by one-way ANOVA

Back to article page

BMC Complementary Medicine and Therapies

ISSN: 2662-7671

Contact us