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Table 2 Enrichment in biological processes

From: The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

GOID

GOTerm

Term PValue

% Associated Genes

Nr. Genes

Associated Genes Found

GO:0006521

regulation of cellular amino acid metabolic process

0.007

4.48

3

[BSG, PSMD6, PSME2]

GO:0016667

oxidoreductase activity, acting on a sulfur group of donors

0.005

5.00

3

[ERO1A, TMX3, TXNDC17]

GO:0071230

cellular response to amino acid stimulus

0.001

5.56

4

[ASS1, COL6A1, LAMTOR5, RRAGA]

GO:0072523

purine-containing compound catabolic process

0.004

5.36

3

[ACOT7, PNP, SAMHD1]

GO:1901569

fatty acid derivative catabolic process

0.000

18.75

3

[ACOT7, LYPLA2, OXCT1]

GO:1901661

quinone metabolic process

0.001

8.11

3

[AKR1B1, CBR3, NDUFA9]

GO:1990928

response to amino acid starvation

0.003

5.88

3

[EIF2AK2, FASN, RRAGA]

GO:0034198

cellular response to amino acid starvation

0.003

6.25

3

[EIF2AK2, FASN, RRAGA]

GO:0070671

response to interleukin-12

0.005

5.08

3

[CDC42, PSME2, SOD2]

GO:0035722

interleukin-12-mediated signaling pathway

0.004

5.36

3

[CDC42, PSME2, SOD2]

GO:0040019

positive regulation of embryonic development

0.002

6.98

3

[AKR1B1, OXSR1, RACK1]

GO:0071470

cellular response to osmotic stress

0.004

5.66

3

[AKR1B1, LETM1, OXSR1]

GO:0051181

cofactor transport

0.005

5.17

3

[BSG, OXSR1, SLC9A3R1]

GO:0072337

modified amino acid transport

0.001

10.00

3

[BSG, OXSR1, SLC9A3R1]

GO:0061245

establishment or maintenance of bipolar cell polarity

0.004

5.66

3

[ARF4, CDC42, SLC9A3R1]

GO:0035088

establishment or maintenance of apical/basal cell polarity

0.004

5.66

3

[ARF4, CDC42, SLC9A3R1]

GO:0045197

establishment or maintenance of epithelial cell apical/basal polarity

0.003

6.25

3

[ARF4, CDC42, SLC9A3R1]

GO:0007006

mitochondrial membrane organization

0.000

4.05

6

[ATP5PB, HSPA4, LETM1, MTX2, NMT1, TIMM13]

GO:0051205

protein insertion into membrane

0.007

4.48

3

[HSPA4, NMT1, TIMM13]

GO:0090151

establishment of protein localization to mitochondrial membrane

0.003

5.88

3

[HSPA4, NMT1, TIMM13]

GO:0051204

protein insertion into mitochondrial membrane

0.003

6.38

3

[HSPA4, NMT1, TIMM13]

GO:1902882

regulation of response to oxidative stress

0.000

4.90

5

[BSG, NONO, RACK1, SOD2, UBQLN1]

GO:1902883

negative regulation of response to oxidative stress

0.000

6.67

4

[BSG, NONO, RACK1, SOD2]

GO:0036473

cell death in response to oxidative stress

0.000

5.00

5

[BSG, NONO, RACK1, SOD2, UBQLN1]

GO:1900407

regulation of cellular response to oxidative stress

0.000

5.38

5

[BSG, NONO, RACK1, SOD2, UBQLN1]

GO:1900408

negative regulation of cellular response to oxidative stress

0.000

6.90

4

[BSG, NONO, RACK1, SOD2]

GO:0008631

intrinsic apoptotic signaling pathway in response to oxidative stress

0.003

6.25

3

[NONO, SOD2, UBQLN1]

GO:1903201

regulation of oxidative stress-induced cell death

0.000

6.33

5

[BSG, NONO, RACK1, SOD2, UBQLN1]

GO:0036475

neuron death in response to oxidative stress

0.001

9.09

3

[BSG, NONO, RACK1]

GO:1903202

negative regulation of oxidative stress-induced cell death

0.000

6.90

4

[BSG, NONO, RACK1, SOD2]

GO:1903203

regulation of oxidative stress-induced neuron death

0.001

10.00

3

[BSG, NONO, RACK1]

GO:1902175

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

0.001

9.68

3

[NONO, SOD2, UBQLN1]

GO:1903204

negative regulation of oxidative stress-induced neuron death

0.000

13.64

3

[BSG, NONO, RACK1]