Potential antiviral effects of some native Iranian medicinal plants extracts and fractions against influenza A virus

Mehrbod, Parvaneh; Safari, Hanieh; Mollai, Zeinab; Fotouhi, Fatemeh; Mirfakhraei, Yasaman; Entezari, Hanieh; Goodarzi, Saied; Tofighi, Zahra

doi:10.1186/s12906-021-03423-x

BMC Complementary Medicine and Therapies

Table 4 Log HA decrement obtained from HA assay

From: Potential antiviral effects of some native Iranian medicinal plants extracts and fractions against influenza A virus

Plant	Extracts or Fractions	Log HA decrement (mean ± SD)
Plant	Extracts or Fractions	Co-pen	Pre-pen	Post-pen
*Glycyrrhiza glabra*	Crude E.	5.00 ± 4.24^abc	4.00 ± 1.41^bc	3.00 ± 0.00^abc
*Glycyrrhiza glabra*	Chloroform F.	1.00 ± 0.00^a	1.00 ± 0.00^a	2.00 ± 1.41^ab
*Glycyrrhiza glabra*	Methanol F.	5.50 ± 3.54^abc	1.50 ± 0.71^a	1.00 ± 0.00^a
*Myrtus communis*	Crude E.	2.50 ± 0.71^ab	2.50 ± 0.71^ab	2.50 ± 0.71^ab
*Myrtus communis*	Chloroform F.	5.50 ± 3.54^abc	4.00 ± 1.41^bc	5.50 ± 3.54^c
*Myrtus communis*	Methanol F.	3.00 ± 1.41^abc	5.50 ± 0.71^c	4.00 ± 0.00^bc
*Melissa officinalis*	Crude E.	3.50 ± 0.71^abc	1.50 ± 0.71^a	1.00 ± 0.00^a
*Melissa officinalis*	Chloroform F.	2.50 ± 0.71^ab	2.50 ± 0.71^ab	2.50 ± 0.71^ab
*Melissa officinalis*	Methanol F.	6.00 ± 2.83^abc	1.00 ± 0.00^a	1.50 ± 0.71^ab
*Hypericum perforatum*	Crude E.	3.00 ± 1.41^abc	2.00 ± 0.00^a	1.00 ± 0.00^a
*Hypericum perforatum*	Chloroform F.	2.50 ± 0.71^ab	2.00 ± 0.00^a	2.50 ± 0.71^ab
*Hypericum perforatum*	Methanol F.	3.00 ± 1.41^abc	2.50 ± 0.71^ab	3.00 ± 1.41^abc
*Tilia platyphyllos*	Crude E.	2.00 ± 0.00^ab	2.00 ± 0.00^abc	3.00 ± 0.00^abc
*Tilia platyphyllos*	Chloroform F.	3.00 ± 1.41^b	2.50 ± 0.71^abc	3.00 ± 0.00^abc
*Tilia platyphyllos*	Methanol F.	4.00 ± 0.00^b	4.00 ± 0.00^c	2.00 ± 0.00^abc
*Salix alba*	Crude E.	4.00 ± 1.41^b	3.50 ± 0.71^bc	4.00 ± 1.41^c
*Salix alba*	Chloroform F.	3.50 ± 0.71^b	2.00 ± 1.41^abc	3.50 ± 0.71^bc
*Salix alba*	Methanol F.	3.00 ± 1.41^b	2.50 ± 2.12^abc	2.50 ± 2.12^abc
*Camellia sinensis*	Crude E.	0.50 ± 0.71^a	1.50 ± 0.71^ab	1.50 ± 0.71^abc
*Camellia sinensis*	Chloroform F.	2.00 ± 0.00^ab	2.50 ± 0.71^ab	1.00 ± 1.41^ab
*Camellia sinensis*	Methanol F.	0.50 ± 0.71^a	0.50 ± 0.71^a	3.00 ± 0.00^abc
*Camellia sinensis* (fermented)	Crude E.	2.50 ± 0.71^ab	2.00 ± 0.00^abc	2.50 ± 0.71^abc
*Camellia sinensis* (fermented)	Chloroform F.	4.00 ± 1.41^b	3.50 ± 2.121^bc	3.50 ± 2.12^bc
*Camellia sinensis* (fermented)	Methanol F.	3.00 ± 0.00^b	2.00 ± 0.00^abc	2.00 ± 0.00^abc
Amantadine hydrochloride	–	7.00 ± 0.00^bc	1.00 ± 0.00^a	1.00 ± 0.00^a
Oseltamivir carboxylate	–	8.00 ± 0.00^c	8.00 ± 0.00^d	8.00 ± 0.00^d

Data presented as mean ± SD are averages of two independent HA titration which were tested in duplicates. Different letters show significant differences in each column (Duncan Grouping)

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