Beneficial effects of ROCEN (Topical Nano-arthrocen) on atopic dermatitis in mice

Table 2 The histological parameters of mice skin subjected to AD in different experiments. Data showed are as mean ± SEM

Experiment	Epithelial thickness (μm)	Collagen deposition %	Angiogenesis No./ mm²	Leucocyte infiltration No./mm²
Oxa	67.74 ± 7.68^C	52.49 ± 4.4^B	4.8 ± 0.54^A	1250 ± 85.63^C
Sham	159.5 ± 33.84	37.01 ± 3.98	3.63 ± 0.66	913.33 ± 76.88
ROCEN+ Oxa	139.8 ± 12.42^b	34.11 ± 3.74^b	3.8 ± 0.23^a	806 ± 51.92^d2
Beta + Oxa	107.77 ± 9.77	43.9 ± 4.14	6.05 ± 1.1	1045 ± 51.85^a

A,B,C,D: Oxa compared with control group. a,b,c,d: treated groups compared with Oxa group. 1,2,3,4: ROCEN compared with Beta group. Aa1; p<0.05, Bb2; p<0.01, Cc3; p<0.001, Dd4; p<0.0001

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