Skip to main content

Table 4 Effect of APHM on biochemical markers of urine after CCl4 induced renal injury in rats

From: Phytochemical, acute toxicity and renal protective appraisal of Ajuga parviflora hydromethanolic leaf extract against CCl4 induced renal injury in rats

Treatment Groups

Doses (mg/kg)

Creatinine (mg/dL)

Urobilinogen (mg/dL)

Urea (mg/dL)

Albumin (mg/dL)

Protein (mg/dL)

Naïve

–

2.74 ± 0.24b

4.38 ± 0.28b

103.22 ± 4.55b

4.56 ± 0.44b

38.47 ± 1.43b

Control

–

5.11 ± 0.65

32.20 ± 2.12

133.55 ± 6.12

18.16 ± 0.85

22.95 ± 1.39

APHMc

100

3.45 ± 0.12a

22.25 ± 1.12a

119.34 ± 3.45a

11.82 ± 0.34a

27.53 ± 1.70

APHM

200

2.34 ± 0.21b

13.62 ± 0.57b

110.76 ± 3.32b

7.42 ± 0.35b

33.82 ± 1.72a

APHM

300

2.56 ± 0.16b

5.04 ± 0.25b

104.14 ± 2.85b

5.08 ± 0.12b

40.14 ± 1.22b

Silymarin

100

2.61 ± 0.20b

10.15 ± 0.85b

105.58 ± 2.46b

6.42 ± 0.22b

35.77 ± 1.44b

  1. Naïve groups did not received any treatment while control received CCl4 only
  2. n = 6, Average values ± SEM,
  3. ap ≤ 0.05 significant as compared to control, bp ≤ 0.005 highly significant as compared to control
  4. cAjuga parviflora hydromethanolic extract