Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice

Table 3 Acetic acid-induced analgesic activity of the crude extract, fractions, and subfractions of I. dipyrena

Treatment	Dose	Number of writhing	% inhibition
Control	(2% Tween 80)	66.19 ± 1.71	–
Crd-Id	100	24.29 ± 2.15^*	63.29
Crd-Id	200	22.28 ± 2.71^**	66.33
Chl-Id	75	21.11 ± 3.19^**	68.14
Et-Id	75	25.57 ± 2.18^**	61.36
Fr.Chl-Id 46	75	20.48 ± 1.78^***	69.03
Fr.Chl-Id 47	75	21.63 ± 2.12^**	67.31
Fr.Chl-Id 48	75	19.73 ± 1.06^***	70.19
Diclofenac	10	11.89 ± 1.41^***	82.03

Each value is represented as Mean ± SEM (n = 8). Where, ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001 statistically significant relative to control. Crd-Id Crude extract, Hex-Id n-hexane fraction, Chl-Id Chloroform fraction; Et-Id Ethyl acetate fraction, Fr.Chl-Id 46, 47 and 48 subfractions

ISSN: 2662-7671