Fig. 3

Effect of STW 5 treatment on the relative abundace of Firmicutes phylum, Enterococcus A, Clostridium B, Lactobacillus C, Balutia D in rats with DSS induced UC. Members of Firmicutes phylum were affected differently. Enterococcus population showed 15-fold increase as compared to vehicle control group and STW 5 treatment completely normalized its level. On the other hand, Clostridium, Lactobacillus and Blautia decreased by 1.3, 3.7 and 1.4 folds (23, 73 and 28%), respectively. STW 5 tended to slightly increase these levels. The microbial concentration expressed as ng per gram of feces was calculated taking 16S rRNA gene copy number into consideration as detailed in the Methods section. Data represented as means ± standard deviation of at least two independent experiments with number of animals of at least 14 animals per group