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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway

Fig. 3

Expression profiles of genes belonging to the PI3K/AKT/mTOR pathway. a Relative expression of PIK3CA, PTEN, AKT1, mTOR, EIF4E, RPS6KB1, and TSC1 in CTRL (non-treated) THP-1 cells. b Heatmap showing changes in gene expression levels during treatments with plant extracts evidenced as fold-change (FC) to non-treated control (CTRL); PIK3CA, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha; PTEN, Phosphatase and Tensin Homolog; AKT1, AKT Serine/Threonine Kinase 1; mTOR, mechanistic Target Of Rapamycin; RPS6KB, Ribosomal Protein S6 Kinase B1; EIF4E, Eukaryotic Translation Initiation Factor 4E; TSC1, TSC Complex Subunit 1

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