Fig. 4

Effects of six ginsenosides on arthritis development in CIA mice after treatment. a The joint images of representative mice in each group at the end of administration. b The arthritis index treated with different ginsenoside as a function of time. Data were expressed as mean ± SD, n = 6. p < 0.05 for each ginsenoside group vs the control group. c Pathological sections of hematoxylin and eosin stained ankle joints in each group, the arrows indicate pannus formation and bone destruction. (Scale bar = 100 μm). PBS and 0.5% Tween was set as normal group and control group, respectively