Group | Bax | Bcl-2 | Bax/Bcl-2 | Caspase-3 | Caspase-9 | Cyclin D1 |
---|---|---|---|---|---|---|
Model control | 1 | 1 | 1 | 1 | 1 | 1 |
5-Fu | 3.36 ± 0.59** | 0.36 ± 0.05** | 9.27 ± 1.01** | 3.60 ± 0.18** | 2.53 ± 0.59** | 1.09 ± 0.27 |
Low-dose | 1.84 ± 0.32* | 0.46 ± 0.19** | 4.47 ± 1.61* | 1.19 ± 0.25 | 2.12 ± 0.27* | 0.36 ± 0.13** |
Medium-dose | 1.66 ± 0.52 | 0.37 ± 0.06** | 4.77 ± 2.30* | 6.47 ± 0.42** | 1.75 ± 0.59 | 0.66 ± 0.31 |
High-dose | 1.63 ± 0.57 | 0.33 ± 0.06** | 5.16 ± 2.19* | 0.91 ± 0.08 | 1.22 ± 0.40 | 0.45 ± 0.17** |