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Table 6 Relative mRNA levels of specific genes involved in apoptosis and proliferation in SGC-7901 xenograft tumor tissues (x ± s, n = 3)

From: A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial–mesenchymal transition via the canonical Wnt/β-catenin signaling pathway

Group

Bax

Bcl-2

Bax/Bcl-2

Caspase-3

Caspase-9

Cyclin D1

Model control

1

1

1

1

1

1

5-Fu

3.36 ± 0.59**

0.36 ± 0.05**

9.27 ± 1.01**

3.60 ± 0.18**

2.53 ± 0.59**

1.09 ± 0.27

Low-dose

1.84 ± 0.32*

0.46 ± 0.19**

4.47 ± 1.61*

1.19 ± 0.25

2.12 ± 0.27*

0.36 ± 0.13**

Medium-dose

1.66 ± 0.52

0.37 ± 0.06**

4.77 ± 2.30*

6.47 ± 0.42**

1.75 ± 0.59

0.66 ± 0.31

High-dose

1.63 ± 0.57

0.33 ± 0.06**

5.16 ± 2.19*

0.91 ± 0.08

1.22 ± 0.40

0.45 ± 0.17**

  1. Data are expressed as fold change. *p < 0.05 vs. model control; **p < 0.01 vs. model control