|
Group
|
Day 4
|
Day 7
|
|---|
|
E.coil
|
Enterococcus
|
Lactobacilli
|
Bifidobacteria
|
E.coil
|
Enterococcus
|
Lactobacilli
|
Bifidobacteria
|
|---|
|
Normal
|
5.45 ± 0.10 **
|
5.21 ± 0.17
|
8.19 ± 0.08
|
8.34 ± 0.13
|
5.55 ± 0.17 **
|
5.27 ± 0.29 *
|
8.76 ± 0.49 *
|
8.87 ± 0.30 *
|
|
Negative control
|
9.00 ± 0.09
|
5.96 ± 0.61
|
8.55 ± 0.46
|
8.38 ± 0.91
|
7.24 ± 0.56
|
6.07 ± 0.47
|
7.77 ± 0.38
|
8.01 ± 0.62
|
|
Loperamide
|
7.27 ± 0.67 **
|
5.83 ± 0.57
|
8.83 ± 0.25
|
8.30 ± 0.93
|
6.20 ± 0.84 **
|
5.93 ± 0.38
|
9.61 ± 0.28 **
|
9.40 ± 0.32 **
|
|
GOS 5%
|
8.40 ± 0.34 *a
|
6.29 ± 0.61
|
8.33 ± 0.80
|
8.40 ± 0.54
|
5.38 ± 0.13 **a
|
5.36 ± 0.32 *
|
9.03 ± 0.50 **
|
9.35 ± 0.38 **
|
|
GOS 10%
|
7.44 ± 0.32 **b
|
6.13 ± 0.67
|
9.02 ± 0.36
|
9.54 ± 0.31
|
5.56 ± 0.38 **a
|
5.31 ± 0.32 *
|
8.89 ± 1.02 *
|
9.74 ± 0.30 **
|
|
GOS 15%
|
8.15 ± 0.26 **a
|
6.26 ± 0.30
|
8.93 ± 0.59
|
9.64 ± 0.44
|
6.43 ± 0.34 *b
|
5.94 ± 0.60 *
|
9.31 ± 0.51 **
|
10.15 ± 0.55 **
|
- Normal, the uninfected-untreated control. Negative control, the infected-untreated control. Loperamide, the infected group with Loperamide-treatment (10 mg/kg). The 5, 10 and 15% GOS were the infected groups treated with corresponding concentration of GOS at a dose of 10 mL/kg, respectively. * P < 0.05 and ** P < 0.01, compared with the negative control. a, b Different letters indicate significant differences existed among the three GOS groups (P < 0.05). Data are presented as mean ± S.E.M, n = 6
