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Table 3 The effect of Otostegia integrifolia extract on diastolic blood pressure in fructose induced hypertensive rat

From: Methanol (80%) leaf extract of Otostegia integrifolia Benth (Lamiaceae) lowers blood pressure in rats through interference with calcium conductance

Group Diastolic BP
Day 0 Day 5 Day 10 Day 15
DF66 89.66 + 5.03 164.54 + 6.69 144.62 + 10.84 143.58 + 4.02
CAP20 88.54 + 4.86 74.91 + 3.85 b3c3d3e3 69.87 + 8.07 b3 c1 65.25 + 3.94 b3
OI250 82.54 + 2.43 132.34 + 10.16 a1 119.25 + 10.83 86.50 + 11.58a3
OI500 90.91 + 6.14 118.61 + 6.78 a3 65.08 + 9.24 a3 f2 87.33 + 2.77 a3
OI1000 86.33 + 5.70 127.75 + 5.37 a2 72.79 + 8.00 a3 f1 85.54 + 5.34 a3
  1. Data are expressed as mean ± SEM (n = 6); Analysis was performed by one-way ANOVA; a, DF66 vs OI; b, DF66 vs CAP20; c, OI250 vs CAP20; d, OI500 vs CAP20; e, OI1000 vs CAP20; f, OI250 vs OI500 and OI100; DF66 Rats with fructose ingestion, CAP20 Captopril 20 mg/kg; OI, Otostegia integrifolia at doses of 250, 500 and 1000 mg/kg; 1p < 0.05; 2p < 0.01; 3p < 0.001.
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