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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Taohuajing reduces oxidative stress and inflammation in diabetic cardiomyopathy through the sirtuin 1/nucleotide-binding oligomerization domain-like receptor protein 3 pathway

Fig. 6

Effects of THJ on the SIRT1 pathway. a. Effects of THJ on the NAD+/NADH ratio in myocardial tissues. b. Detection of protein expression levels of Ac-SOD2, SIRT1, and Ac- FOXO3a using western blotting. c. Mice were treated with the SIRT1 inhibitor sirtinol for 12 weeks and treated with THJ. The effects of THJ on SIRT1 expression levels were assessed. d. DHE intensity levels after treatment with the SIRT1 inhibitor sirtinol. e. Effects of sirtinol on MDA levels. F. Effects of sirtinol on SOD levels. Values are shown as means ± standard deviations from three different experiments. ##P < 0.01 versus the Con group, **P < 0.01 versus the DCM group, &&P < 0.01 versus the THJ group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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