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Table 2 Topological parameters for key targets of RA-SLE-ADR (Top 10 by degree)

From: Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

Name

Degree

Betweenness Centrality

Closeness Centrality

IL6

42

0.08073

0.8889

STAT3

39

0.05424

0.8421

TNF

39

0.05274

0.8421

VEGFA

38

0.03849

0.8276

TP53

37

0.03982

0.8136

MMP9

33

0.04720

0.7619

CCND1

33

0.02525

0.7619

PTGS2

32

0.01696

0.7500

IL4

32

0.02743

0.7500

IL2

30

0.02124

0.7273