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Table 1 The anti-HCV activity (IC50) and cytotoxicity (CC50) of compounds isolated from M. latifolia fruit extract

From: Alkaloid and benzopyran compounds of Melicope latifolia fruit exhibit anti-hepatitis C virus activities

Sample

IC50 (μg/ml)

CC50 (μg/ml)

SI

O-methyloktadrenolon

10.9 ± 1.2

63 ± 2.3

5.8

Alloevodionol

41.1 ± 3.1

> 1000

> 24.3

Isopimpinellin

> 50

> 1000

> 20

Alloxanthoxyletin

21.72 ± 2.2

93 ± 3.0

4.3

Methylevodionol

> 50

310 ± 2.5

> 6.2

N-methylflindersine

3.8 ± 2.7

97 ± 3.3

25.5

  1. Data represent mean ± SD of triplicate experiments