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Table 1 The anti-HCV activity (IC50) and cytotoxicity (CC50) of compounds isolated from M. latifolia fruit extract

From: Alkaloid and benzopyran compounds of Melicope latifolia fruit exhibit anti-hepatitis C virus activities

Sample IC50 (μg/ml) CC50 (μg/ml) SI
O-methyloktadrenolon 10.9 ± 1.2 63 ± 2.3 5.8
Alloevodionol 41.1 ± 3.1 > 1000 > 24.3
Isopimpinellin > 50 > 1000 > 20
Alloxanthoxyletin 21.72 ± 2.2 93 ± 3.0 4.3
Methylevodionol > 50 310 ± 2.5 > 6.2
N-methylflindersine 3.8 ± 2.7 97 ± 3.3 25.5
  1. Data represent mean ± SD of triplicate experiments