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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: RETRACTED ARTICLE: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression

Fig. 8

Treatment with SSB extract increased the expression levels of miR-124 in LPS/D-GalN-induced acute liver injury in mice. 24 h after the administration of LPS/D-GalN plus SSB extract, the miR-124 expression in LPS/D-GalN-induced mouse liver was determined via RT-PCR and in situ hybridization. a Representative in situ hybridization showing the level of miR-124 expression in liver tissue 24 h after the administration of LPS/D-GalN plus SSB. b–c: Representative RT-PCR and statistical summary of the densitometric analysis of miR-124 expression in the liver tissue 24 h after the administration of LPS/D-GalN plus SSB extract. Data are expressed as the mean ± SD. *P < 0.05: compared with the control group; #P < 0.05 and ##P < 0.01: compared with the model group. P > 0.05: control group compared with the control treatment group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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