Fig. 4
Protective effect of lianzixin extracts on the viability of caffeine treated PC12 cells. Caffeine significantly decreased cell viability compared to the normal control group. Neferine 1.88 and 6.25 mg/mL, total alkaloids 1 and 3 mg/mL, alcohol extract 3 mg/mL, and water extract 3 mg/mL inhibited the decrease in cell viability induced by caffeine. **P < 0.01 caffeine versus normal control group; # P < 0.05 lianzixin extracts or neferine versus caffeine treatment group; ## P < 0.01 lianzixin extracts or neferine versus caffeine treatment group