Fig. 1

Effect of M. subcordata extracts on viability and luciferase activity of U2OS-Cytotox and U2OS-PPARγ cells. Showing the effect after 24 h exposure to rosiglitazone (RG,10 μM), enzyme hydrolysed (eh) and non-hydrolysed (nh) methanol extracts of fruit, leaf, root and seed of M. subcordata tested at a concentration of 30 gDW/L. Cell viability (a) was measured by the resazurin assay with the viability of cells exposed to the solvent control (1% DMSO) set at 100%, and luciferase activity (b) was measured by the CALUX reporter gene assay and expressed as fold induction compared to solvent control. Data are presented as mean ± SD` of three independent experiments. Asterisks indicate a significant difference from the solvent control: *p < 0.05; **p < 0.01; ***p < 0.001