Fig. 8
From: Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
Analysis of CMC1 and CMC7 binding to monomeric α-syn by NMR spectroscopy. a Proton-nitrogen correlation (HSQC) spectra b averaged NMR chemical shift perturbation of 1H/15N resonances, and c Residue-specific NMR signal intensity ratios of α-syn in the absence and presence of increasing stoichiometries of CMC1 (CMC1: α-syn of 0:1, 1:1, 2:1, 4:1, 6:1, 10:1, and 20:1). d Proton-nitrogen correlation (HSQC) spectra and e Residue-specific NMR signal intensity ratios of α-syn in the absence and presence of increasing stoichiometries of CMC7 (CMC7: α-syn of 0:1, 1:1, 2:1, 4:1, 6:1, and 10:1)