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Table 1 Percent of inhibition of inflammation, endothelial activation, NF-κB and eNOS biomarkers by each FD variety based on area under the curve (AUC) analysis

From: Ficus deltoidea suppresses endothelial activation, inflammation, monocytes adhesion and oxidative stress via NF-κB and eNOS pathways in stimulated human coronary artery endothelial cells

 

VCAM-1% inhibition

ICAM-1% inhibition

E-selectin % inhibition

IL-6% inhibition

NF-κB p50% inhibition

NF-κB p65% inhibition

eNOS % increment

P

G

P

G

P

G

P

G

P (N)

P (C)

G

P (N)

P (C)

G

P

G

FDT

59.4

77.7

33.8

8.1

75.4

76.5

66.0

69.2

6.4

10.3

85.3

39.4

10.4

200.9

15.7

−100.1

FDK

52.8

82.0

24.5

22.1

74.3

75.2

65.5

67.3

5.1

10.3

87.6

34.9

16.8

330.8

15.1

−100.0

FDD

38.8

46.3

18.1

−8.2

56.3

27.3

31.5

39.1

10.0

12.6

72.1

7.6

19.5

1046.1

−4.8

−99.1

FDI

4.7

53.5

10.5

10.8

49.7

74.9

25.3

60.9

4.3

8.0

82.8

11.1

12.4

103.8

2.6

−100.1

  1. FDT FD var. trengganuensis, FDK FD var. kunstleri, FDD FD var. deltoidea, FDI FD var. intermedia, P protein, G gene, N nuclear lysate, C cytoplasmic lysate, bold, first and second most potent FD varieties