Vochysia tucanorum Mart. butanol fraction presents antitumoral activity in vivo and prevents the installation of cachexia in solid Ehrlich tumor model

Table 2 Body weight at the beginning (day 1), middle (day 7) and final (day 15) of the treatment with 100 mg/kg (TV100), 200 mg/kg (TV200) or 400 mg/kg (TV400) of Fr-BuVt

	Day 1 (g)	Day 7 (g)	Day 15 (g)	Weight ratio (%)
CS	45.35 ± 1.07	46.72 ± 1.11	47.82 ± 1.31	+ 5.44
TS	47.01 ± 1.17	47.55 ± 1.27	44.52 ± 1.08	− 5.29
TV100	46.79 ± 1.00	47.14 ± 1.23	46.07 ± 1.12	− 1.53
TV200	46.53 ± 1.23	48.15 ± 1.14	48.99 ± 1.17	+ 5.28
TV400	47.93 ± 1.4	49.13 ± 1.39	50.09 ± 1.49	+ 4.5

CS (Control animals treated with saline; TS (Ehrlich carcinoma-bearing mice treated with saline); TV100 (Ehrlich carcinoma-bearing mice treated with 100 mg/kg Fr-BuVt); TV200 (Ehrlich carcinoma-bearing mice treated with 200 mg/kg Fr-BuVt); TV400 (Ehrlich carcinoma-bearing mice treated with 400 mg/kg Fr-BuVt). Values are expressed as means ± SEM. There are no significative differences between groups in the same day, one-way ANOVA followed by Holm-Sidak post hoc test.

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