Fig. 5

The effects of ASA VI on the protein expression levels of p-ERK1/2, p-smad2/3, ERK1/2 and smad2/3. Western blot analysis of p-ERK1/2、p-Smad2/3 、ERK1/2 and smad2/3 expression levels after treatment with ASA VI for 48 h. p-ERK1/2 and p-Smad2/3 levels were normalized to those of ERK1/2 and smad2/3(Fig. 5b) and the protain levels of ERK1/2 and smad2/3 were folded of control (Fig. 5c). ** p < 0.01 vs controls