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Table 3 Minimal inhibitory and bactericidal concentrations of different sub-fractions

From: Bark extract of Cassia sieberiana DC. (Caesalpiniaceae) displayed good antibacterial activity against MDR gram-negative phenotypes in the presence of phenylalanine-arginine β-naphthylamide

Bacterial strains

Sub-fractions and concentrations (μg/mL)

CSBc1

CSBc2

CSBc3

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

Escherichia coli

 ATCC8739

256

> 2

64

64

1

256

> 2

 AG102

nt

nd

256

> 2

64

> 8

Klebsiella pneumoniae

 ATCC11296

64

> 8

128

> 4

nt

nd

 KP55

nt

nd

nt

nd

nt

nd

Enterobacter aerogenes

 ATCC13048

512

> 1

256

> 2

nt

nd

 EA27

nt

nd

nt

nd

nt

nd

Providencia stuartii

 ATCC29916

nt

nd

256

> 2

256

> 2

 PS2636

nt

nd

256

> 2

nt

nd

Pseudomonas aeruginosa

 PA01

nt

nd

nt

nd

nt

nd

 PA124

nt

nd

128

128

1

nt

nd

 PSBS (%)

30

  

70

  

30

  
  1. MIC minimal inhibitory concentration, MBC minimal bactericidal concentration R: MBC / MIC ratio (a sample is considered as bacteriostatic or bactericidal when this ratio is > 4 or ≤ 4 respectively) (−): MIC or MBC > 512 μg/mL nt: not tested nd: not determined (as no MIC and MBC values were not observed till 512 μg/mL) PBSS: percentage of susceptible bacteria to substances CSBc1, CSBc2 and CSBc3 are sub-fractions from fraction CSBc