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Table 2 Minimal inhibitory and bactericidal concentrations of crude extract, his derived fractions and chloramphenicol

From: Bark extract of Cassia sieberiana DC. (Caesalpiniaceae) displayed good antibacterial activity against MDR gram-negative phenotypes in the presence of phenylalanine-arginine β-naphthylamide

Bacterial strains

Tested samples and concentrations (μg/mL)

CSB

CSBa

CSBb

CSBc

Chloramphenicol

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

Escherichia coli

 ATCC8739

512

512

1

512

512

1

–

nt

nd

128

128

1

2

64

32

 AG102

512

512

1

–

nt

nd

–

nt

nd

512

512

1

32

256

8

Klebsiella pneumoniae

 ATCC11296

512

–

> 1

512

512

1

–

nt

nd

512

–

> 1

32

256

8

 KP55

128

512

4

512

512

1

–

nt

nd

128

512

4

64

256

4

Enterobacter aerogenes

 ATCC13048

512

512

1

–

nt

nd

–

nt

nd

512

512

1

16

128

8

 EA27

–

nt

nd

–

nt

nd

–

nt

nd

–

nt

nd

32

256

8

Providencia stuartii

 ATCC29916

512

512

1

–

nt

nd

512

512

1

512

512

1

64

256

4

 PS2636

512

512

1

–

nt

nd

512

512

1

512

512

1

64

256

4

Pseudomonas aeruginosa

 PA01

512

–

> 1

–

nt

nd

–

nt

nd

512

–

> 1

64

–

> 4

 PA124

512

512

1

–

nt

nd

–

nt

nd

512

512

1

64

–

> 4

 PSBS (%)

90

  

30

  

20

  

90

  

100

  
  1. MIC minimal inhibitory concentration, MBC minimal bactericidal concentration R: MBC / MIC ratio (a sample is considered as bacteriostatic or bactericidal when this ratio is > 4 or ≤ 4 respectively) (−): MIC or MBC > 512 μg/mL for crude extract and fractions and > 256 for chloramphenicol nt: not tested nd: not determined (as no MIC and MBC values were not observed till 512 μg/mL) PBSS: percentage of susceptible bacteria to substances CSB is crude extract of Cassia sieberiana CSBa, CSBb and CSBc are fractions from CSB
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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