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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivo

Fig. 4

Effect of JPYW on BGC823/5-Fu in vitro. a. MTT assay showed that JPYW had a proliferation inhibition effect on BGC823/5-Fu, and the inhibition effect increased with the increase of concentration; b. The expression of MDR1 mRNA gradually decreased after JPYW treated BGC823/5-Fu cells, and the inhibitory effect was enhanced when combined with LY294002; c. The ratio of p-AKT expression and AKT expression dose-dependent decreased after the treatment of JPYW, also when combined with pathway inhibitor LY294002 (P < 0.05)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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