Fig. 5

Effect of HESAE on aconitase activity and MMP in PC-12 cells treated with high-dose corticosterone. a Aconitase activity and b MMP were evaluated by aconitase and MMP assays following pre-treatment with HESAE for 48 h and high-dose corticosterone of 400 μM for 24 h. Data are expressed as mean ± SD and statistically analysed by Tukey’s test. Asterisks (*) and hash signs (#) indicate significant differences (p < 0.05) in aconitase activity and MMP compared to the corticosterone group and desipramine group, respectively