Cardioprotective potential of polyphenols rich Thraatchathi Chooranam against isoproterenol induced myocardial necrosis in experimental rats

Table 3 Effect of TC on membrane stabilizing enzymes in heart tissue normal and ISO induced rats

Treatment	Na⁺ / K⁺ ATPase (μg/min/mg protein)	Ca²⁺ ATPase (μg/min/mg protein)	Mg²⁺ ATPase (μg/min/mg protein)
Normal Control	38.49 ± 3.18	27.62 ± 1.17	29.13 ± 1.58
Isoproterenol (120 mg/kg)	15.14 ± 1.54^##	40.74 ± 3.40^##	17.54 ± 1.91^##
Vitamin E (100 mg/kg)	32.39 ± 2.87**	26.64 ± 1.57**	23.30 ± 1.39
Low dose TC (50 mg/kg)	26.23 ± 2.30*	24.63 ± 1.97*	25.61 ± 1.44*
High Dose TC (100 mg/kg)	29.83 ± 1.18**	24.84 ± 2.42**	27.55 ± 2.26**
Drug Control TC (100 mg/kg)	37.36 ± 2.66	30.35 ± 2.37	22.04 ± 1.27

The results are expressed as mean ± SEM (n = 6/group); mean differences between the groups was analyzed using one-way ANOVA with Tukey test for multiple comparison # and ## denotes p < 0.05 and p < 0.01, respectively, when compared with normal control group *and** denotes p < 0.05 and p < 0.01, respectively, when compared to isoproterenol group. p ≤ 0.05 is considered as statistically significant. Biostatistical analysis was performed using GraphPad Prism 5.0 Version

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