Xanthine oxidase inhibitory activity of a new isocoumarin obtained from Marantodes pumilum var. pumila leaves

Table 1 Percentages of xanthine oxidase inhibition of extracts of Marantodes pumilum varieties and allopurinol

Species	Plant part	Crude extracts	Yield (%)	Percentage of xanthine oxidase inhibition (%)^a
M. pumilum var. alata	Roots	DCM	0.85	0.00
		MeOH	8.08	0.00
		H₂O	6.00	0.00
	Leaves	DCM	1.80	68.21 ± 2.50
		MeOH	2.23	41.15 ± 4.31
		H₂O	2.74	0.00
M. pumilum var. pumila	Roots	DCM	1.59	0.00
		MeOH	4.63	0.00
		H₂O	2.58	0.00
	Leaves	DCM	1.38	85.77 ± 0.70
		MeOH	1.09	80.97 ± 0.72
		H₂O	4.56	0.00
M. pumilum var. lanceolata	Roots	DCM	3.16	0.00
		MeOH	7.21	0.00
		H₂O	5.16	0.00
	Leaves	DCM	3.30	74.33 ± 4.33
		MeOH	8.70	67.52 ± 0.35
		H₂O	1.03	0.00
Allopurinol (positive control)				99.82 ± 0.00

Data are presented as mean ± S.E.M. of three replicates (n = 3)
^aPercentage of xanthine oxidase inhibition of extracts and allopurinol were determined at concentration of 400 μg/mL and 100 μg/mL, respectively

ISSN: 2662-7671