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Table 2 The comparisons of the mean knee pain at three measurement time points

From: The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial

Measurement Group P value (t-test) RM ANOVA Mixed model analysis with interaction a,b
Intervention, Mean ± SD Placebo, Mean ± SD   Parameter P value Parameter Estimate P value
Baseline pain 6.86 ± 1.60 6.25 ± 1.61 0.111 Time 0.001 Intercept 5.527 .000
Pain after 4 weeks 5.22 ± 1.70 5.69 ± 1.52 0.221 Group 0.001 Baseline pain 0.733 .000
Pain after 6 weeks 4.52 ± 1.78 5.66 ± 1.65 0.006 Group×time 0.001 Time −0.494 .080
Intervention group −1.133 .006
Baseline pain ×group −.712 .002
Baseline pain×time −0.018 .233
  1. a. Control group is set as the reference group
  2. b. Dependent Variable: Pain