The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial

Table 2 The comparisons of the mean knee pain at three measurement time points

Measurement	Group		P value (t-test)	RM ANOVA		Mixed model analysis with interaction ^a,b
Measurement	Intervention, Mean ± SD	Placebo, Mean ± SD		Parameter	P value	Parameter	Estimate	P value
Baseline pain	6.86 ± 1.60	6.25 ± 1.61	0.111	Time	0.001	Intercept	5.527	.000
Pain after 4 weeks	5.22 ± 1.70	5.69 ± 1.52	0.221	Group	0.001	Baseline pain	0.733	.000
Pain after 6 weeks	4.52 ± 1.78	5.66 ± 1.65	0.006	Group×time	0.001	Time	−0.494	.080
						Intervention group	−1.133	.006
						Baseline pain ×group	−.712	.002
						Baseline pain×time	−0.018	.233