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Table 7 Effect of PA flower ethanolic extracts on HBA1c %, Insulin, and C-peptide in diabetic rats

From: Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Groups/Treatment/Dose

(n = 10)

HBA1c (%)

Insulin (mlU/L)

C-Peptide (ng/ml)

Normal Control/1 ml/kg

4.4 ± 0.02

35.2 ± 0.46

0.98 ± 0.016

Diabetic Control/1 ml/kg

10.8 ± 0.12***

18.30 ± 0.36***

0.45 ± 0.012a

Diabetic-PA/150 mg/kg

7.5 ± 0.19***, ###

25.30 ± 0.47***, ###

0.66 ± 0.011a, b

Diabetic-PA/300 mg/kg

6.12 ± 0.11***, ###

30.8 ± 0.48***, ###

0.86 ± 0.011a, b

Diabetic-Met/150 mg/kg

4.8 ± 0.10a, ###

31.9 ± 0.43***, ###

0.90 ± 0.009a, b

  1. Values are expressed as mean ± SEM; n = 10. ∗∗∗ p < 0.001 significant vs. Normal Control. ###p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control, b; non-significant vs. Diabetic Control. HBA1c Glycosylated hemoglobin; PA Plicosepalus acacia; Met Metformin