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Table 3 Major metabolite changes observed in normal control (MC) and cisplatin-induced of NRK-52E culture media

From: NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition

No.

Metabolite

δH ppm (multiplicity)

Fold changes

Metabolic pathway

1

Alanine

1.48 (d)

1.10***

Amino acid metabolism

2

Ethanol

1.17 (t), 3.65 (dd)

0.57**

Glycolysis

3

Glucose

5.22 (d)

1.05***

Glycolysis

4

Lactate

1.30 (d)

0.93**

Glycolysis

5

Pyruvate

3.36 (s)

1.14***

Glycolysis

  1. ***p < 0.0001, **p < 0.001