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Table 3 Major metabolite changes observed in normal control (MC) and cisplatin-induced of NRK-52E culture media

From: NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition

No. Metabolite δH ppm (multiplicity) Fold changes Metabolic pathway
1 Alanine 1.48 (d) 1.10*** Amino acid metabolism
2 Ethanol 1.17 (t), 3.65 (dd) 0.57** Glycolysis
3 Glucose 5.22 (d) 1.05*** Glycolysis
4 Lactate 1.30 (d) 0.93** Glycolysis
5 Pyruvate 3.36 (s) 1.14*** Glycolysis
  1. ***p < 0.0001, **p < 0.001