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Table 6 Effects of sub-chronic oral administration of ICR on the lipid profile of males rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Males ICR (mg/kg b.w.)
Control 250 500 1000
TC (mmol/L) 1.499 ± 0.100 1.699 ± 0.008 ns 1.876 ± 0.062 ns 1.378 ± 0.034 ns
TG (mmol/L) 1.167 ± 0.072 1.21 ± 0.028ns 1.435 ± 0.221 ns 1.248 ± 0.157 ns
HDL (mmol/L) 2.193 ± 0.088 2.13 ± 0.052 ns 2.425 ± 0.034ns 2.043 ± 0.199ns
LDL (mmol/L) 0.537 ± 0.110 0.343 ± 0.016* 0.5233 ± 0.023 ns 0.645 ± 0.024 ns
  1. Results were expressed as Mean ± SEM for n = 5 animals per group. *:Significantly different from the control at p < 0.05
  2. TC Total cholesterol, TG Total triglyceride, HDL High density lipoprotein, LDL Low density lipoprotein, ns non significative, ICR methanol extract of the roots of Imperata cylindrica