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Table 6 Effects of sub-chronic oral administration of ICR on the lipid profile of males rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Males

ICR (mg/kg b.w.)

Control

250

500

1000

TC (mmol/L)

1.499 ± 0.100

1.699 ± 0.008 ns

1.876 ± 0.062 ns

1.378 ± 0.034 ns

TG (mmol/L)

1.167 ± 0.072

1.21 ± 0.028ns

1.435 ± 0.221 ns

1.248 ± 0.157 ns

HDL (mmol/L)

2.193 ± 0.088

2.13 ± 0.052 ns

2.425 ± 0.034ns

2.043 ± 0.199ns

LDL (mmol/L)

0.537 ± 0.110

0.343 ± 0.016*

0.5233 ± 0.023 ns

0.645 ± 0.024 ns

  1. Results were expressed as Mean ± SEM for n = 5 animals per group. *:Significantly different from the control at p < 0.05
  2. TC Total cholesterol, TG Total triglyceride, HDL High density lipoprotein, LDL Low density lipoprotein, ns non significative, ICR methanol extract of the roots of Imperata cylindrica
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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