Females | ICR (mg/kg b.w.) | |||
---|---|---|---|---|
Control | 250 | 500 | 1000 | |
Serum creatinine (μmol/l) | 53.670 ± 3.969 | 46.300 ± 4.210 ns | 52.620 ± 2.977 ns | 48.41 ± 3.930 ns |
Urinary creatinine (μmol/l) | 1049 ± 67.97 | 1159 ± 52.730ns | 475.600 ± 44.200* | 994.900 ± 55.250ns |
Serum urea (mmol/L) | 6.733 ± 0.026 | 6.113 ± 0.733ns | 3.455 ± 0.131ns | 6.762 ± 0.7427ns |
Urinary urea (mmol/L) | 10.739 ± 0.024 | 11.46 ± 1.260ns | 12.100 ± 0.5764ns | 12.080 ± 0.8529ns |
Serum total protein (g/L) | 44.800 ± 0.034 | 43.300 ± 0.062ns | 34.500 ± 0.056ns | 42.300 ± 0.007ns |
Urinary total protein (g/L) | 7.239 ± 0.277 | 6.800 ± 0.036 ns | 7.687 ± 0.241 ns | 6.606 ± 0.434 ns |
ALT (U/L) | 33.350 ± 1.521 | 31.650 ± 2.260 ns | 35.200 ± 1.218 ns | 31.830 ± 1.701 ns |
AST (U/L) | 74.740 ± 3.420 | 58.220 ± 2.019* | 58.270 ± 2.399* | 52.100 ± 2.895* |