|
Parameter
|
Sham
|
PCOS control
|
Metformin
|
Caraway
|
Thylakoids
|
P- value
|
|---|
|
TG (mg/dl)
|
40.81 ± 5.07a
|
63.72 ± 3.25b
|
48.6 ± 4.9c
|
46.45 ± 4.76c
|
49 ± 3.16c
|
< 0.001*
|
|
TC (mg/dl)
|
41.45 ± 1.96a
|
64.81 ± 3.15b
|
50.3 ± 4.13c
|
48.72 ± 4.1c
|
49.9 ± 2.94c
|
< 0.001*
|
|
LDL_C (mg/dl)
|
14.27 ± 1.1a
|
23.18 ± 2.22b
|
16.5 ± 1.5dc
|
15.27 ± 2ad
|
16.81 ± 0.98c
|
< 0.001*
|
|
HDL_C (mg/dl)
|
21.18 ± 2.27a
|
13.18 ± 0.87b
|
13.9 ± 1.19b
|
16.09 ± 1.04c
|
13.9 ± 0.83b
|
< 0.001*
|
|
FBS (mg/dl)
|
95.9 ± 4.52a
|
151.27 ± 11.76b
|
115.3 ± 3.65c
|
118.36 ± 4.43c
|
119.27 ± 3.43c
|
< 0.001*
|
|
Insulin (mIU/L)
|
11.1 ± 3.79a
|
14.88 ± 3.76a
|
12.15 ± 4.29a
|
13.39 ± 6.14a
|
12.96 ± 3.74a
|
0.36
|
|
HOMA − IR
|
2.62 ± 0.90a
|
5.51 ± 1.33b
|
3.48 ± 1.28ac
|
3.92 ± 1.8c
|
3.8 ± 1.04c
|
< 0.001*
|
|
TNFα (pg/ml)
|
103.60 ± 35.13a
|
148.62 ± 21.95b
|
115.11 ± 24.10a
|
107.55 ± 41.19a
|
105.75 ± 32.85a
|
0.04*
|
|
MDA (pg/ml)
|
2.29 ± 0.1a
|
3.19 ± 0.2b
|
2.6 ± 0.28c
|
2.64 ± 0.18c
|
2.52 ± 0.28c
|
< 0.001*
|
|
LH (mIU/mL)
|
9.96 ± 3.01a
|
18.96 ± 4.29b
|
13.53 ± 2.97a
|
14.14 ± 4.31a
|
14.04 ± 7.21a
|
0.003*
|
|
FSH (IU/mL)
|
17.86 ± 3.45a
|
22.85 ± 9.61a
|
23.19 ± 7.32a
|
22.36 ± 5.77a
|
22.44 ± 7.17a
|
0.37
|
- Sham Non PCOS induced rats that received distilled water, PCOS control PCOS induced rats that received distilled water, Metformin PCOS induced rats that received metformin, Caraway PCOS induced rats that received caraway aqueous extract, Thylakoids PCOS induced rats that received thylakoid extract, TG Triglyceride, TC Total Cholesterol, LDL_C Low density lipoprotein, HDL_C High density lipoprotein, FBS Fasting blood sugar, HOMA−IR Homeostatic model assessment-insulin resistance, TNFα Tumor necrosis factor alpha, MDA Malondialdehyde, LH Luteinizing hormone, FSH Follicle-stimulating hormone
- Data expressed as Mean ± SD, In each row, figures bearing different superscripts are significantly different at p < 0.05 (one way ANOVA)
