Fig. 5From: PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for gliomaPAMs reduced tumor growth and increased survival in intracranial mouse GL-26 glioma C57BL/6 mouse model. Mice were implanted intracranial with mouse glioma GL-26 cells and treated with PAMs (48 mg/kg) or vehicle for 14 days. PAMs treated mice (a) reduced tumor size, b reduced tumor weight, and c inhibited MAO A catalytic activity in tumor compared to vehicle control. PAMs treated mice also had (d) increased survival compared to vehicle control. Each group n = 5Back to article page