Fig. 6From: Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-κB and PI3K-Akt signaling networksEffects of NF-κB, MAPKs and Akt inhibitors in LPS-activated U937 macrophages; BAY 11–7082 (NF-κB inhibitor), U0126 (ERK inhibitor), SB202190 (p38 inhibitor), SP600125 (JNK inhibitor), LY294002 (Akt inhibitor) on TNF-α production and COX-2 protein expression. ###p < 0.001 represents the significant difference from the control. *p < 0.05, **p < 0.01, and ***p < 0.001 represent significance to the TCE pretreated versus inhibitors treatment. All values are stated as mean ± SEM (n = 3)Back to article page