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Table 5 List of compounds identified in the Second Chloroform Layer (SCL) fraction and their presence (P) in other fractions obtained from SCL

From: Assessment of antidiabetic potential and phytochemical profiling of Rhazya stricta root extracts

RT Compounds identified in SCL fraction Fractions obtained from SCL   
H4 N6 N7 P1 Q1 S3 S4c U2 V4 W5 Synonyms (PubChem CID) Reported Antidiabetic/ Antioxidant Activity
4.039 2H-Pyran, tetrahydro-2-(12-pentadecynyloxy)-         P     
5.441 Azocine, octahydro- P     P P       
5 .802 8-Azabicyclo[3.2.1]oct-2-ene P    P   P   P     
5.866 2-Amino-6-methoxypyridine             
5.996 4(1H)-Pyridinone, 2,3-dihydro-1-methyl-        P      
6.271 Tetratetracontane             
7.263 Pyridine, 3-ethyl-5-methyl-        P   P    
7.346 1,3-Propanediol, 2-butyl-2-ethyl-          P    
7.665 Nonane, 4,5-dimethyl- P P P    P       
9.095 Hexadecane P P    P P   P P    
9.736 Dodecane, 4,6-dimethyl- P P P   P P       
10.238 Dodecane, 1-iodo-   P P   P P       
10.658 1-(3-Aminopropyl)-2-pipecoline P P P   P P   P P P   
10.720 2-Isopropyl-5-methyl-1-heptanol P P P   P P       
10.864 Dodecane, 1-iodo- P P P   P P       
10.990 Dodecane, 2,7,10-trimethyl- P   P    P       
11.08 4,4′-Isopropylidenebis (3-methyl-2-isoxazolin-5-one)        P   P    
11.360 Cyclohexanamine, N-methyl-n-propyl- P P   P P P P P P    
11.596 Acetamide, 2-(3-hydroxy-8-aza-bicyclo [3.2.1]oct-8-yl)-N-(2,4,6-trimethylphenyl)- P     P P P      
11.874 1H-Isoindole-1,3(2H)-dione, hexahydro-          P    
12.332 n-Hexadecane   P     P       Inhibition of enzymes involved in glucose metabolism [40]
12.641 Heptacosane P   P   P P       
12.871 Decane, 2,3,5,8-tetramethyl-        P      
12.981 Quinoline, 2,4-dimethyl-     P      P    
13.063 Eicosane, 1-iodo- P   P       P    
13.178 Heptacosane P   P    P       
13.293 2,4-Di-tert-butylphenol P P   P P P P   P P   
13.345 ((8R,8aS)-8-Isopropyl-5-methyl-3,4,6,7, 8,8a-hexahydronaphthalen-2-yl)-methanol             
13.411 11-Methyldodecanol P    P    P      
13.528 1-Decanol, 2-hexyl-      P        
13.606 Heptacosane P P    P P       
13.737 Cyclohexane, 1-ethyl-2-propyl- P      P       
13.911 1-Naphthalenamine, N-ethyl-     P      P P   
13.961 3′,5′-Dimethoxyacetophenone      P        
14.041 Guanethidine P    P     P     
14.714 Heptadecane, 2,6,10,15-tetramethyl-             
14.134 Pyridine, 3-methyl-4-phenyl-        P   P    
14.287 Heptacosane        P      
15.119 Humulene             
15.212 Heptacosane P P    P P       
15.278 Heptadecane, 2,6,10,15-tetramethyl-   P    P P       
15.560 2-Bromotetradecane       P       
15.682 1-Naphthalenamine, N-ethyl-             
15.887 2-Tetradecanol             
15.980 Carbonic acid, eicosyl vinyl ester P     P        
16.028 Dodecane, 1-iodo- P     P        
16.127 Heptacosane             
16.185 1,7-Dimethyl-4-(1-methylethyl)cyclodecane P   P          
16.280 Methoxyacetic acid, 2-pentadecyl ester             
16.487 Thiourea,(5,5-dimethyl-3-oxo-5,6-dihydropyrrolo[2,1-a]isoquinolin-2-ylidene)-       P       
16.540 11-Methyldodecanol P            
16.852 Sydnone, 3-(2-naphthyl)-             
16.958 Ethanone, 2-chloro-1H-indol-1-yl- P   P    P       
17.028 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, methyl ester   P P          
17.139 1H-Indole, 4-(3-methyl-2-butenyl)-             
17.288 1,2-Benzenedicarboxylic acid, bis(2-ethylpropyl) ester        P   P    
17.458 Eicosane, 1-iodo-             
17.547 Pyrrolidine-2,5-dione, 1-(3-chlorophenyl)-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)- P P P P P P P P   P   
17.584 (6-Methylquinolin-2-yl)methanamine    P P         
17.714 Heptacosane P   P   P P       
17.797 Hexadecanoic acid, methyl ester     P         
17.833 1,7-Dimethylene-2,3-dimethylindole             
18.032 Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester    P   P P       
18.096 Isobutyl tetradecyl ether             
18.156 n-Hexadecanoic acid P P P   P P       Antidiabetic [41]
18.211 Eicosane, 1-iodo-      P P       
18.370 Hexadecane    P          
18.666 Carbonic acid, eicosyl vinyl ester P   P    P       
19.479 trans-13-Octadecenoic acid, methyl ester   P         P   Antioxidant [42]
19.526 9-Octadecenoic acid (Z)-, methyl ester P P P P P P P P     Antioxidant [42]
19.630 Hexadecane       P       
19.699 Methyl stearate P   P P P        
19.839 9,12-Octadecadienoic acid (Z,Z)-   P P P P    P     
19.862 3-Amino-5-chloro-benzofuran-2-carboxylic acid methyl ester             
20.443 Heptacosane, 1-chloro-      P P P   P    
20.502 o-(2,4-Dinitrostyryl)-phenol   P           
20.932 Aspidofractinine P      P       
20.986 Aspidospermidine, 1,2-didehydro-, (5.alpha., 12.beta.,19.alpha.)-   P P P P   P   P P   
21.053 Carbonic acid, octadecyl vinyl ester P P    P P     P   
21.193 Heptadecane, 8-methyl-             
21.445 Eicosanoic acid, methyl ester     P         
21.662 Heptadecane, 8-methyl-             
21.722 Octadecane, 3-ethyl-5-(2-ethylbutyl)- P P P   P P P   P P   
21.779 Oxiranedodecanoic acid, 3-octyl-, cis-             
21.891 Fumaric acid, monoamide, N,N-dimethyl-, 1-naphthyl ester             
22.039 .beta.-Hydroxyquebrachamine P    P P P       
22.053 Hexanedioic acid, bis(2-ethylhexyl) ester   P P P P P P P P    
22.157 Chromium, (1-methoxy-3,3-diphenylpropylidene) pentacarbonyl-             
22.317 5,8-Dimethylquinoxaline             
22.335 Acetic acid, 6-morpholin-4-yl-9-oxobicyclo[3.3.1]non-3-yl ester           P   
22.483 1,2,5-Oxadiazole-3-carboxamide, 4-amino-N-[2-[[(3-chlorophenyl) methyl] amino] ethyl]-     P     P     
22.548 Naphtho[1,2-b]furane-2,8-dione, 2,3,3a,4,5,5a,8,9b-octahydro-9-methyl-3-(3,3-dimethyl-1-piperidylmethyl)- P   P P P P P P P    
22.595 (.+/−.)-Uleine             Antioxidant [43]
22.664 Apparicine, Nb-methyltetrahydro-             
22.686 octadecanoic acid, 3-oxo-, ethyl ester             
22.843 1H-Cyclopent[ij]indolo[2,3-a] quinolizine,13a-ethyl-2,3,5,6,6a,11,12, 13,13a,13b-decahydro-11-methyl-, [6aR-(6a.alpha.,11aS*,13a.beta.,13b. beta.)]-            Vallesamidine (579878)  
22.859 2,20-Cyclo-8,9-secoaspidospermidine, 3-methyl-, (2.alpha., 3.beta.,5.alpha., 12. beta., 19.alpha.,20R)-             
22.894 1-Methyl-16-methoxyaspidospermidin-4-one P            
22.997 12H-benzo[b]phenoxazine, 12-methyl-             
23.061 Methyl 8-methyl-nonanoate P    P P    P     
23.169 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, 13a-ethyl-2,3,5,6,13a,13b-hexahydro- P P P P P P P P    Eburnamenine(13aR-cis)-610,470)  
23.169 2-Methyl-7-phenylindole             
23.195 Eburnamenin-14-ol, 14,15-dihydro-, (14.beta.)-    P         14-Isoeburnamine (619344)  
23.218 Quebrachamine P P P P P P P P P    
23.440 l-Alanine, n-propargyloxycarbonyl-, ethyl ester P P   P P    P     
23.806 2,4-Diamino-6-methyl-1,3,5-triazine             
23.899 Indolo[2,3-a]quinolizin-4(12H)-one, 1,2,3,6,7,12b-hexahydro-3,12b-dimethyl-    P          
24.029 Aspidospermidine, 1-ethyl-    P   P        
24.165 Eburnamenine-14-methanol, 14,15-dihydro-, (3.alpha.,14.alpha.,16.alpha.)-         P    Vincaminol (201188)  
24.360 Akuammilan-17-oic acid, methyl ester P   P P P   P   P   Strictamine (5324377)  
24.647 2H-3,7-Methanoazacycloundecino[5,4-b]indole-9-carboxylic acid, 5-ethyl-1,4,5,6,7,8,9,10-octahydro-, methyl ester, [5S-(5R*,7R*,9S*)]-            Cleavamine (425980)  
24.761 Phthalic acid, 2-ethylbutyl nonyl ester    P          
25.092 Vinburnine P P P P P    P    Eburnamonine (71203) Antidiabetic [44]
25.817 Phthalic acid, bis(7-methyloctyl) ester    P     P      
26.081 Squalene    P   P P P P P    Antidiabetic [45] Antioxidant [46]
26.328 Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3.alpha.,14.alpha.,16.alpha.)-           P Vincamine (15376) Antidiabetic Activity [44]
26.766 Apovincamine   P P    P