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Table 2 Sedative activity of dinaphthodiospyrol G isolated from D. lots

From: In vivo analgesic, anti-inflammatory, and sedative activity and a molecular docking study of dinaphthodiospyrol G isolated from Diospyros lotus

Treatment

Doses (mg/kg)

Line crossed

Diazepam

0.5

6.86Ā Ā±Ā 0.11***

Chloroform extract

50

104.54Ā Ā±Ā 2.00

100

99.60Ā Ā±Ā 2.34

200

96.20Ā Ā±Ā 2.70

Dinaphthodiospyrol G

2.5

88.98Ā Ā±Ā 1.86*

5

74.00Ā Ā±Ā 1.58**

10

62.98Ā Ā±Ā 1.32**

15

51.98Ā Ā±Ā 1.20***

  1. Data expressed as the meanā€‰Ā±ā€‰standard error of the mean (S.E.M.) of number of lines crossed for each group (nā€‰=ā€‰6), statistically, analysis of variance (one way) was done followed by multiple comparison through Dunnettā€™s post-hoc test; Where, pā€‰<ā€‰0.05ā€‰=ā€‰*; pā€‰<ā€‰0.01ā€‰=ā€‰**; pā€‰<ā€‰0.001ā€‰=ā€‰***.