Fig. 1

Curcumin inhibited CCL3 production in OCPs. (a-c) After treatment with different concentrations of curcumin for 12 h, the levels of CCL2, CCL3 or CX3CL1 secreted from OCPs are assessed by ELISA assays. (d-f) After treatment with different concentrations of curcumin for 12 h in the presence of RANKL, the levels of CCL2, CCL3 or CX3CL1 secreted from OCPs are assessed by ELISA assays. (a-f) Compared among each group, ^lettersP < 0.05 by one-way ANOVA. (g, h) After treatment with different concentrations of curcumin for 8 h in the presence or absence of RANKL, the protein levels of CCL3 in the OCPs are detected by Western Blotting. Compared among each group, ^lettersP < 0.05 by one-way ANOVA. Data are expressed as mean ± SEM from three independent experiments. CUR, curcumin