Fig. 1

Qiliqiangxin (QLQX) improves survival rate and cardiac function after myocardial infarction (MI). a: Survival rate. FVB/NJ mice were subjected to sham or MI operation. The number of dead mice over a 4-wk period was counted daily. Survival curves were analyzed with the Kaplan-Meier tests. Data are presented as mean ± SD, ^#compared to saline group, P < 0.05, n = 10 per group. b: Echocardiogram analysis. Representative echocardiographic images of FVB/NJ mice 4 weeks after MI surgery. c: QLQX improves cardiac function including preserving left ventricular fractional shortening (LVFS) and left ventricular ejection fraction (LVEF). Data are presented as mean ± SD, ^**compared to Sham group, P < 0.01, ^# compared to saline group, P < 0.05, n = 8 per group. d: Evan’s blue/TTC stain. Heart tissue sections were stained with Evan’s blue/TTC at 4 weeks after MI surgery. The infarct area (INF: white) and area at risk (AAR: red); blue is the normal myocardial blood supply area. e: The ratio of INF/AAR and AAR/LV. Data are presented as mean ± SD, ^# compared to saline group, P < 0.05, n = 6 per group. The comparison of measurement data between two groups was carried out by independent-sample T test