Table 2 Enzymes Inhibition Activities of B. pacumbis
From: Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor
Extracting Solvents | IC50 Values (μg/mL) | ||||||
|---|---|---|---|---|---|---|---|
α-Amylase | α-Glucosidase | Lipase | Tyrosinase | Elastase | AChE | BChE | |
Hexane | NI | NI | 447.86 ± 19.58 | NI | NI | NI | NI |
Ethyl Acetate | 29.91 ± 0.22 | 2.49 ± 0.01 | 121.71 ± 5.75 | 280.36 ± 1.56 | 174.34 ± 1.44 | 36.79 ± 2.66 | 14.83 ± 1.88 |
Methanol | 14.03 ± 0.04 | 0.29 ± 0.00 | 67.26 ± 0.17 | 58.25 ± 1.63 | 74.00 ± 3.03 | 31.52 ± 0.58 | 11.69 ± 0.14 |
Water | 43.77 ± 0.54 | 3.54 ± 0.00 | 445.202 ± 2.15 | 168.81 ± 0.56 | NI | 104.37 ± 1.88 | 76.99 ± 0.37 |
Acarbose | 20.12 ± 0.12 | 261.23 ± 9.10 | – | – | – | – | – |
Kojic Acid | – | – | – | 18.39 ± 0.15 | – | – | – |
Orlistat | – | – | 431.58 ± 13.82 | – | – | – | – |
Quercetin | – | – | – | – | 101.23 ± 0.16 | – | – |
Galantamine | – | – | – | – | – | 1.09 ± 0.02 | 26.27 ± 1.41 |