Fig. 5From: Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expressionEffects of JPYW on FEN1 expression and cleavage ability. JPYW directly inhibited FEN1 expression of BGC823/5-Fu cells at both (a) gene level and (b) protein level. c JPYW inhibited the activity of FEN1 at the enzymatic level .The top part showed the synthetic 32p labeled DNA substrates. The middle showed PAGE-separated products and the bottom showed the cleavage percentage at different JPYW concentrationsBack to article page