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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression

Fig. 5

Effects of JPYW on FEN1 expression and cleavage ability. JPYW directly inhibited FEN1 expression of BGC823/5-Fu cells at both (a) gene level and (b) protein level. c JPYW inhibited the activity of FEN1 at the enzymatic level .The top part showed the synthetic 32p labeled DNA substrates. The middle showed PAGE-separated products and the bottom showed the cleavage percentage at different JPYW concentrations

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