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Table 1 The general information of the included studies

From: Methodological and reporting quality evaluation of meta-analyses on the Chinese herbal preparation Zheng Qing Feng Tong Ning for the treatment of rheumatoid arthritis

StudyLanguagePublication formNumber of documents (case number)Intervention measures (control vs treatment)OutcomesAMSTAR2 (point)PRIMSA (point)
Xu 2008 [20]EnglishJournal10 (1185)SIN vs single NSAIDs;
SIN vs combined NSAIDs
(1) NIP; (2) NRP; (3) MS; (4) PJ; (5) SJ; (6) GS; (7) ESR; (8) CPR; (9) JTS; (10) AI617
Qi 2010 [30]ChineseJournal3 (280)ZQFTN vs MTX;(1) MS; (2) SJ; (3) PJ; (4) ESR; (5) RF;416
Zhang 2012 [31]ChineseJournal10 (1365)NSAIDs + MTX + ZQFTN vs NSAIDs + MTX;
MTX + ZQFTN vs MTX;
NSAIDs + MTX + PED + ZQFTN vs NSAIDs + MTX + PED;
MTX + SSZ + ZQFTN vs MTX + SSZ;
LEF + MTX + ZQFTN vs LEF + MTX;
(1) ACR; (2) PJ; (3) SJ; (4) ESR; (5) CPR; (6) RF;717.5
Li 2012 [32]ChineseJournal8 (735)ZQFTN + MTX vs MTX(1) Total Effect; (2) MS; (3) ESR; (4) RF; (5) CRP; (6) Adverse Effects515.5
Wang 2015 [33]ChineseJournal6 (476)ZQFTN + NSAIDs + MTX vs NSAIDs + MTX;
ZQFTN vs OXA;
ZQFTN + SSZ vs MTX + SSZ;
ZQFTN + MTX vs MTX;
ZQFTN + MTX vs MTX + D-Pen;
ZQFTN + NSAIDS + MTX vs NSAIDs + MTX;
(1) Total Effect; (2) Adverse Effects; (3) MS; (4) ESR; (5) CPR; (6) RF;819
Chen 2015 [34]EnglishJournal11 (956)ZQFTN+MTX vs MTX;(1) RF; (2) CPR; (3) ESR; (4) SJ; (5) MS616
Li 2016 [35]ChineseJournal8 (708)NSAIDS + ZQFTN + MTX vs NSAIDs + MTX;
ZQFTN + SSZ vs MTX + SSZ;
ZQFTN + MTX vs MTX;
ZQFTN + MTX vs MTX + D-Pen;
ZQFTN + LEF + NSAIDS vs LEF + NSAIDs
(1) Total Effect; (2) Adverse Effects; (3) MS; (4) PJ; (5) GS; (6) SJ; (7) ESR; (8) RF; (9) CPR;720.5
Liu 2016 [21]EnglishJournal16 (1500)ZQFTN vs MTX;
ZQFTN + MTX vs MTX;
Basic therapy + ZQFTN + MTX vs Basic therapy + MTX
(1) Clinical efficacy; (2) MS; (3) Total clinical effective rate in 4 weeks treatment; (4) SJ; (5) GS; (6) ESR; (7) CPR; (8) Blood platelet; (9) DAS28;1020
  1. Abbreviations: SIN Sinomenine preparations, NSAIDs Non-steroidal anti-inflammatory drugs, NIP Number of improved patients, NRP Number of rheumatoid-factor-disappeared patients, MS Morning stiffness, PJ Painful joint, SJ Swollen joint, GS Grip strength, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, JTS Joint tenderness score, AI Articular index, ZQFTN Zhengqing Fengtongning release tablets, MTX Methotrexate, LEF Leflunomide, D-pen D-penicillamine, SSZ Sulfasalazine, PED Prednisone, ACR American college of rheumatology, RF Rheumatoid factor, DAS28 Disease activity score-28