Fig. 2

a) Western blot profiles showing the effect of AME treatment on protein expression of p53, Bcl2, and caspase 3 in tumor tissues compared with the (untreated) EST and negative control groups. B-actin was used as internal control protein. b-d) Band quantification of p53 (b), caspase 3 (c) and Bcl2 (d) proteins expression after treatment by AME with two doses. Data are expressed as mean ± SEM (n = 7). Values with different superscript letters [a (the highest value) – c (the lowest value)] in each graph are significantly different at p < 0.05. All groups were compared to each other for each protein. G1, negative control group; G2, EST group; G3, low dose AME (180 mg/ Kg)-treated group; G4, high dose AME (360 mg/ Kg) -treated group